Module 1: The Foundations of Health and Longevity; The Gut Microbiome.

This module aims to:

• Introduce the link between aesthetic presentations and the foundational mechanisms underlying all chronic conditions; dysbiosis, inflammation, metabolic dysfunction, and neuroendocrine alterations.
• Introduce the hallmarks of ageing and the concept of inflammageing
• Discuss the different levels of scientific evidence and how to differentiate between headlines and fine print.
• Introduce the gut microbiome and what is believed to be a healthy gut microbial composition.
• Provide an overview of the key microbial phyla and species involved in human health and longevity.
• Introduce microbial metabolites' expansive and crucial key roles in supporting human physiology.
• Define the link between dysbiosis and disease states, focusing on obesity and chronic conditions linked to dermatological manifestations.
• Discuss key factors involved in the evolution and modification of the gut microbiome across the lifespan, including the unique microbiome of the supercentenarian.
• Introduce prebiotics and probiotics as microbial modulators.

Module 2: The Gut-Skin Axis; The Microbiome in Aesthetic Presentations

This module aims to:

• Present the biological complexity of aesthetic presentations.
• Introduce the link between diet, the microbiome and gut health.
• Explore the molecular mechanisms by which microbial metabolites regulate gut wall integrity and initiate systemic signals to support distal organs.
• Discuss how microbial metabolites communicate with the innate and adaptive immune systems to maintain immune tolerance throughout the body.
• Explain the current understanding of the Gut-Skin Axis and how the microbiome supports skin homeostasis.
• Present the link between dysbiosis, leaky gut, inflammation, and aesthetic presentations.
• Detail the pathogenic role of endotoxin and specific microbial profiles in obesity and allergic, autoimmune, and inflammatory dermatological presentations.
• Provide examples of the gut-skin connection in pathological states and how this may increase the risk of complications following cosmetic treatments.
• Outline how nutritional strategies can improve microbial composition and gut-skin communication pathways.
• Provide evidence for using prebiotics, probiotics, vitamins, polyphenols and amino acids as therapeutics for aesthetic conditions.
  

Module 3: Nutrients for Microbial Modulation and Epigenetic Reprogramming

This module aims to:

• Introduce the crucial role of nutrients in the human body.
• Discuss the extent of nutrient deficiencies and how they relate to aesthetic signs and symptoms.
• Define the epigenome and its key components.
• Present the interaction between nutrients and the epigenome and how this relates to health outcomes.
• Introduce the concept of gene polymorphisms and their role in nutrient processing and availability.
• Discuss the role of macronutrients, micronutrients, dietary compounds, and popular diets in shaping the microbiome.
• Explain how the microbiome contributes to nutrient status.
• Introduce autophagy, cellular senescence, telomere attrition and the dietary factors that regulate or influence these mechanisms.
• Discuss how nutrient deficiencies and certain dietary compounds like lectins and dairy may be linked to aesthetic signs and symptoms. 
• Present the findings from research conducted on collagen powders.
• Understand what to look for when choosing supplements for your practice.

Module 4: Supporting Mitochondria for Aesthetic Outcomes and Longevity

This module aims to:

• Discuss the mechanical model of the hallmarks of ageing as a therapeutic framework.
• Present the research to support the crucial role of mitochondria in longevity.
• Explore mitochondrial function regarding energy production, oxidative stress management and cellular homeostasis regulation.
• Discuss how nutrients regulate mitochondrial processes and their essential role as cofactors for the mitochondrial chain.
• Introduce the concept of mitophagy and expand on autophagy.
• Introduce the antioxidant pathways involved in scavenging free radicals to reduce oxidative stress. 
• Explain the bidirectional pathways between the gut microbiome and mitochondria and how this interaction supports longevity under physiological conditions.
• Define the pathogenesis and prevalence of mitochondrial dysfunction. Present the current understanding of the role of mitochondrial dysfunction in ageing and aesthetic presentations with a focus on lipedema.
• Discuss the limitations of research into the effects of oral nutrients on health and aesthetic outcomes.
• Discuss evidence-based nutritional strategies for optimising mitochondrial function.

Module 5: Nutritional Interventions to Support Detoxification Pathways

This module aims to:

• Discuss how and why our toxin exposure is increasing and why a "safe" level of toxins may not be safe at all.
• Highlight the importance of supporting detoxification to reduce oxidative stress and prevent toxicity's many signs and symptoms.
• Present the evidence linking toxins to endocrine and metabolic disorders.
• Look at how toxins are hidden in food and nutraceuticals and how they impact the microbiome.
• Explain why artificial sweeteners are just as bad as sugar.
• Discuss the link between advanced glycation end products, polycystic ovarian syndrome, and skin ageing.
• Summarise detoxification pathways in the gut and liver and the nutritional compounds that can support the process and prevent toxin recycling.
• Discuss the role of antioxidants and dietary interventions in reducing oxidative stress during weight loss.
• Understand the Gut-Liver Axis and the pathogenesis of fatty liver disease.
• Present the link between fatty liver disease and aesthetic presentations.
• Summarise the steps involved in detoxification and how to systematically support the process with nutritional interventions, nutrients and antioxidants.

Module 6: Weight Management for Health and Longevity

This module aims to:

• Understand the complexity of weight management and why long-term success needs a multisystem approach.
• Identify the main factors involved in energy balance and appetite control.
• Learn how the body utilises and stores energy and the factors that influence or disrupt these processes.
• Understand the many signals involved in the sensation of satiety and hunger and how these can be disrupted.
• Discuss the past and current understanding of the Set-weight theory and how weight homeostasis is maintained.
• Provide a detailed look at ghrelin, leptin and insulin and the modifiable factors that regulate them.
• Understand the importance of optimising glycaemic control and how the microbiome helps to regulate it.
• Explain how leptin and insulin resistance develops and how these pathological states influence body weight and skin presentations.
• Differentiate between adipose tissue subtypes; white, brown, beige, obese and lipedema fat.
• Explain the mechanisms by which the body burns fat and the factors that assist the process.
• Explore the many roles of the gut microbiome in weight management.
• Understand the multifactorial pathogenesis of resistance to fat loss.
• Discuss the current stance on personalised nutrition and precision medicine and the most valuable tests and biological trackers that can guide the personalisation of nutritional interventions.
• Summarise the dietary and nutritional interventions that assist with achieving and maintaining a healthy body weight.

Module 7: The Gut-Brain Axis; Optimising Brain Function & Neuroplasticity

This module aims to:

• Introduce the Gut-Brain Axis and the many ways in which the gut microbiota communicates with the brain.
• Understand how a healthy gut microbiome influences mood, behaviour, cognitive function, neuroplasticity and habit formation.
• Introduce the concept of vagal tone and the evidence to support vagal stimulation for stress-related disorders.
• Describe the pathways and dietary factors that contribute to neuroinflammation.
• Present the evidence for the link between dysbiosis and mood disorders, cognitive decline, altered stress response, sleep disorders and addictions. 
• Explain the Gut-Brain-Skin connection and how stress is linked to aesthetic presentations.
• Explore the role of estrogen in skin health.
• Understand the pathogenesis of food addiction and why overcoming maladaptive behaviours is essential for health and longevity.
• Present the role of neuroplasticity in habit formation and the factors that influence it.
• Summarise the evidence supporting using nutritional strategies to optimise brain function and develop healthy habits.

Module 8: Injectable Nutrients in The Aesthetic Setting

This module aims to:

• Present the current evidence and understanding of injectable nutrients.
• Highlight the importance of training, education, and experienced supervision to ensure patient safety.
• Discuss the evidence for and against the use of:
•    Intramuscular B-group vitamins and vitamin D
•    Intravenous NAD versus oral NAD precursors
•    Intravenous versus oral glutathione
•    Intravenous versus oral vitamin C
• Summarise a framework for safely implementing certain oral and injectable nutrients in the aesthetic setting.
  

Upon completion of the course, you will receive:

• A Certificate of Completion, which may attract CPD points*
• On-demand access to all modules for a period determined by the course provider. 
• Slides for each module.
• Training and support to help you create a passive online income using nutrient therapies and streamlined personalised nutritional programs.*

* Please check with your college or institution.

** Training is offered through Bio-Alai® on account set up